Blogs & Interviews

A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity

A CPI grant funded Dr. Kotsopoulos at the University of Toronto, Toronto, Canada for Evaluating BRCA1 haploinsufficiency as a putative target for the prevention of BRCA1-associated cancer. She and her collaborators developed a cell-based test to...

In Memory of Dr. Charis Eng

Charis Eng 1962-2024...

Li Fraumeni Syndrome and one family’s harrowing experience with this deadly disease

Li Fraumeni (LF) is a hereditary cancer syndrome due to deleterious inherited mutations in the TP53 gene that increases the risk for developing a wide range of cancers, mostly sarcomas, breast cancers, brain tumors, and leukemias. In the Wall...

Expert Interview with Alan Venook, MD, on colorectal cancer and the promise of immunotherapy for prevention and treatment

Posted February 9, 2023 - Dr. Alan Venook is a nationally renowned expert in gastrointestinal cancers such as colorectal cancer (CRC) and liver cancer. He is based at University of California, San Francisco (UCSF) and holds the Madden Family...

Expert Interview with David Reese, MD, on cancer prevention and precision medicine

Posted June 23, 2022 - Dr. David Reese is Executive Vice President, Research and Development (R&D) at Amgen. In his current role, he oversees Discovery Research, Global Development, Global Regulatory Affairs and Safety, and Global Medical....

Expert Interview with Ray Deshaies, PhD, on drug development and cancer therapeutics

Posted on March 14, 2022 - Dr. Ray Deshaies is Senior Vice President of Global Research at Amgen and a Visiting Associate at the California Institute of Technology (Caltech). Prior to joining Amgen, Dr. Deshaies received his BS in...

Expert Interview with Peter P. Lee, MD, on “Immune chemoprevention for breast cancer via repurposing a low-cost, safe, anti-parasitic drug”

Posted on January 02, 2021 - Dr. Peter P. Lee is Chair of the Department of Immuno-Oncology and co-leader of the Cancer Immunotherapeutics Program at the City of Hope Comprehensive Cancer Center in Duarte, CA. He is the recipient of the 2019,...

Expert Interview with Charis Eng, MD, PhD, on “Genetic testing, a personalized tool to build a roadmap to manage inherited cancers”

Posted on November 09, 2020 - Dr. Charis Eng is the Director of the Genomic Medicine Institute and its Center for Personalized Genetic Healthcare at the Cleveland Clinic. Her clinical and basic research teams use state-of-the-art technologies...

Expert Interview with Heather Hampel, MS, LGC, on Genetic Testing and Lynch Syndrome

Posted on October 01, 2020 - Professor Heather Hampel is the Associate Director of the Division of Human Genetics at the Ohio State University. She is a cancer genetic counselor, and an expert on Lynch syndrome. Heather Hampel has published over...

Expert Interview with Ian M. Thompson Jr., MD, on the Prostate Cancer Prevention Trial

Posted on September 02, 2020 - Dr. Ian Thompson Jr. is a renowned urologic oncologist and visionary whose work is transforming prostate cancer care. He is the President of the CHRISTUS Santa Rosa (CSR) Medical Center Hospital and Vice...

Expert interview with Michael B. Sporn, MD, the “Father of Chemoprevention”, on cancer prevention

Posted on August 05, 2020 - Michael B. Sporn is an Emeritus Professor of Pharmacology, Toxicology and Medicine at Dartmouth Geisel School of Medicine. Before that, he was Chief of the Laboratory of Chemoprevention at the National Cancer...

Expert interview with Daniel Fleming Hayes, MD, on biomarkers for breast cancer

Posted on July 01, 2020 - Dr. Hayes is Professor of Breast Cancer Research and Internal Medicine at the University of Michigan Rogel Cancer Center, Ann Arbor, MI. He is a world-renowned medical researcher and oncologist in the field of breast...

Expert Interview with Professor Jack Cuzick, PhD, on medicines for the prevention of breast cancer

Posted June 03, 2020 - Professor Jack Cuzick is the Director of the Wolfson Institute of Preventive Medicine and Head of the Centre for Cancer Prevention in London, UK. He is a pioneer in the field of cancer prevention. His work has played a...

Expert Interview with Joe Miletich, MD, PhD, on vaccines for cancer prevention

Posted May 13, 2020 - Joe Miletich is the Senior Vice President of Research Sciences at Merck Research Laboratories. He is an expert drug developer whose personal life and career have intersected with HPV. His older sister died of cervical cancer...

Preventing disease to prolong life…

Posted May 04, 2020 - Preventing disease to prolong life... Our friend Roger Horchow died on Saturday, May 2, 2020, at 11:36 am. Roger was obsessed with prevention in a variety of ways. He prevented forgetfulness by keeping records of...